Early Detection Of Polycystic Ovarian Disease Using Optimized Machine Learning Technique
DOI:
https://doi.org/10.29284/ijasis.12.1s.2026.210-232Keywords:
polycystic ovary disease, Tarsier Optimization Algorithm, progressive ANN, Predictive Model.Abstract
Polycystic ovary syndrome (PCOS) and polycystic ovary disorder (PCOD) are widespread endocrine conditions affecting millions of women around the world. These disorders can result in considerable reproductive challenges and metabolic complications. By providing the urgent need for effective and accessible diagnostic methodologies, the proposed study aims to enhance the efficiency and interpretability of Artificial Neural Network (ANN) techniques for the early detection of these conditions through innovative data pre-processing strategies and progressive training data modules. This research addresses a critical gap in the literature by systematically identifying and eliminating noisy data during the pre-processing phase. The Tarsier Optimization Algorithm (TOA), inspired by the adaptive behaviours of Tarsiers is introduced to facilitate efficient exploration of the solution space. This approach refines the dataset used in model training while emphasizing the importance of feature significance. By leveraging TOA's adaptive strategies, the clarity and performances of the progressive ANN (PANN-TOA) are improved, ensuring robust handling of noisy data. The methodology highlights the necessity of optimizing data processing to deepen the understanding of the complex manifestations and health outcomes associated with PCOS and PCOD. Ultimately, the new work aims to provide a robust framework that enhances diagnostic accuracy of about 95% and informs personalized treatment strategies, paving the way for improved reproductive health outcomes and empowering individuals to make informed health decisions. Thus, the results show that the PANN performed better than previous machine learning (ML) models, demonstrating its capacity to identify intricate patterns in clinical data.
References
1. Maqbool, M., Ara, I. and Gani, I., 2022. The story of polycystic ovarian syndrome: a challenging disorder with numerous consequences for females of reproductive age. International Journal of Current Research in Physiology and Pharmacology, pp.19-31.
2. Ali, A.T., Al-Ani, O., Al-Ani, F. and Guidozzi, F., 2022. Polycystic ovary syndrome and metabolic disorders: A review of the literature. African Journal of Reproductive Health, 26(8), pp.89-99.
3. Zhu, T., Cui, J. and Goodarzi, M.O., 2021. Polycystic ovary syndrome and risk of type 2 diabetes, coronary heart disease, and stroke. Diabetes, 70(2), pp.627-637.
4. Kiconco, S., Teede, H.J., Azziz, R., Norman, R.J. and Joham, A.E., 2021, July. The need to reassess the diagnosis of polycystic ovary syndrome (PCOS): a review of diagnostic recommendations from the international evidence-based guideline for the assessment and management of PCOS. In Seminars in reproductive medicine (Vol. 39, No. 03/04, pp. 071-077). Thieme Medical Publishers, Inc..
5. Presswala, B. and De Souza, L.R., 2023. The diagnostic experience of polycystic ovary syndrome: a scoping review of patient perspectives. Patient Education and Counseling, 113, p.107771.
6. Rao, V.S., Cowan, S., Armour, M., Smith, C.A., Cheema, B.S., Moran, L., Lim, S., Gupta, S., Manincor, M.D., Sreedhar, V. and Ee, C., 2022. A Global Survey of ethnic Indian women living with polycystic ovary Syndrome: co-morbidities, concerns, diagnosis experiences, Quality of Life, and Use of Treatment methods. International Journal of Environmental Research and Public Health, 19(23), p.15850.
7. Verma, P., Maan, P., Gautam, R. and Arora, T., 2024. Unveiling the Role of Artificial Intelligence (AI) in Polycystic Ovary Syndrome (PCOS) Diagnosis: A Comprehensive Review. Reproductive Sciences, pp.1-15.
8. Khanwalkar, P., Preethi, M., Divya, K. and Keerthana, K.R., 2024, April. AI-driven Detection of PCOS for Personalized Health Improvement. In 2024 International Conference on Knowledge Engineering and Communication Systems (ICKECS) (Vol. 1, pp. 1-6). IEEE.
9. Zigarelli, A., Jia, Z. and Lee, H., 2022. Machine-aided self-diagnostic prediction models for polycystic ovary syndrome: observational study. JMIR Formative Research, 6(3), p.e29967.
10. Alam Suha, S.A.Y.M.A., 2022. Predicting Polycystic Ovary Syndrome through Machine Learning Technique Using Patients’ symptom Data and Ovary Ultrasound Images (Doctoral dissertation, Department of Computer Science and Engineering, MIST)
11. Sydora, B.C., Wilke, M.S., McPherson, M., Chambers, S., Ghosh, M. and Vine, D.F., 2023. Challenges in diagnosis and health care in polycystic ovary syndrome in Canada: a patient view to improve health care. BMC Women's Health, 23(1), p.569.
12. Gupta, R., Tanwar, S., Tyagi, S. and Kumar, N., 2020. Machine learning models for secure data analytics: A taxonomy and threat model. Computer Communications, 153, pp.406-440.
13. Lin, H., Xue, Y., Chen, K., Zhong, S. and Chen, L., 2022. Acute coronary syndrome risk prediction based on gradient boosted tree feature selection and recursive feature elimination: A dataset-specific modeling study. Plos one, 17(11), p.e0278217.
14. Sharma, T., Mohapatra, A.K. and Tomar, G., 2023. A novel SVM and LOF-based outlier detection routing algorithm for improving the stability period and overall network lifetime of WSN. International Journal of Nanotechnology, 20(5-10), pp.759-789.
15. Modi, K., Singh, I. and Kumar, Y., 2023. A comprehensive analysis of artificial intelligence techniques for the prediction and prognosis of lifestyle diseases. Archives of Computational Methods in Engineering, 30(8), pp.4733-4756.
16. Stafie, C.S., Sufaru, I.G., Ghiciuc, C.M., Stafie, I.I., Sufaru, E.C., Solomon, S.M. and Hancianu, M., 2023. Exploring the intersection of artificial intelligence and clinical healthcare: a multidisciplinary review. Diagnostics, 13(12), p.1995.
17. Meng, C., Trinh, L., Xu, N., Enouen, J. and Liu, Y., 2022. Interpretability and fairness evaluation of deep learning models on MIMIC-IV dataset. Scientific Reports, 12(1), p.7166.
18. Wagner, M.W., Namdar, K., Biswas, A., Monah, S., Khalvati, F. and Ertl-Wagner, B.B., 2021. Radiomics, machine learning, and artificial intelligence—what the neuroradiologist needs to know. Neuroradiology, pp.1-11.
19. McNamara, M.E., Zisser, M., Beevers, C.G. and Shumake, J., 2022. Not just “big” data: Importance of sample size, measurement error, and uninformative predictors for developing prognostic models for digital interventions. Behaviour research and therapy, 153, p.104086.
20. Wang, R., Gu, Z., Wang, Y., Yin, X., Liu, W., Chen, W., Huang, Y., Wu, J., Yang, S., Feng, L. and Zhou, L., 2022. A “one‐stop shop” decision tree for diagnosing and phenotyping polycystic ovarian syndrome on serum metabolic fingerprints. Advanced Functional Materials, 32(45), p.2206670.
21. Anand, S., Kumar, A., Prasad, A. and Trivedi, K., 2022. Updated meta‐analysis on the diagnostic accuracy of serum anti‐Mullerian hormone in poly cystic ovary syndrome involving 13 509 subjects. Journal of Obstetrics and Gynaecology Research, 48(8), pp.2162-2174.
22. Lakshmi, M.J., Spandana, D.S., Raj, H., Niharika, G., Kodipalli, A., Kamal, S. and Rao, T., 2023, April. Prediction of PCOS and PCOD in Women Using ML Algorithms. In International Conference on Information and Communication Technology for Intelligent Systems (pp. 97-115). Singapore: Springer Nature Singapore.
23. Gaur, Y., Chaudhary, A. and Abraham, A., 2023, December. Analysing Polycystic Ovary Syndrome Using Machine Learning Models. In International Conference on Intelligent Systems Design and Applications (pp. 467-475). Cham: Springer Nature Switzerland.
24. Kite, C., 2020. The effectiveness of exercise in the treatment of polycystic ovary syndrome (Doctoral dissertation, Aston University).
25. Hasan, S.S., 2021. Evaluation of Vaspin Levels and Some Biochemical Variables in poly cystic Ovary Syndrome Patients in Diyala Governorate (Doctoral dissertation, College of Science Department of Chemistry Evaluation of Vaspin Levels and Some Biochemical Variables in poly cystic Ovary Syndrome Patients in Diyala Governorate A Thesis Submitted to the Council of the College of Science, University of Diyala).
26. Bansal, C., Handa, P. and Goel, N., 2023, September. Comparing different models for polycystic ovary syndrome diagnosis: An empirical investigation on a large clinical dataset. In 2023 IEEE Women in Technology Conference (WINTECHCON) (pp. 1-6). IEEE.
27. Srinithi, V. and Rekha, R., 2023, February. Machine learning for diagnosis of polycystic ovarian syndrome (PCOS/PCOD). In 2023 International Conference on Intelligent Systems for Communication, IoT and Security (ICISCoIS) (pp. 19-24). IEEE.
28. Sinthia, G., Poovizhi, T. and Khilar, R., 2022. Analysis on polycystic ovarian syndrome and comparative study of different machine learning algorithms. In Advances in Intelligent Computing and Communication: Proceedings of ICAC 2021 (pp. 191-196). Singapore: Springer Nature Singapore.
29. Tiwari, S., Kane, L., Koundal, D., Jain, A., Alhudhaif, A., Polat, K., Zaguia, A., Alenezi, F. and Althubiti, S.A., 2022. SPOSDS: A smart Polycystic Ovary Syndrome diagnostic system using machine learning. Expert Systems with Applications, 203, p.117592.
30. Kumar, A., Singh, J. and Khan, A.A., 2024. A comprehensive machine learning framework with particle swarm optimization for improved polycystic ovary syndrome (PCOS) diagnosis. Engineering Research Express, 6(3), p.035233.
31. Dutta, P., Paul, S. and Majumder, M., 2021. An efficient SMOTE based machine learning classification for prediction & detection of PCOS.
32. Paramasivam, G.B. and Ramasamy Rajammal, R., 2024. Modelling a self-defined CNN for effectual classification of PCOS from ultrasound images. Technology and Health Care, 32(5), pp.2893-2909.
33. Jain, P., Mishra, R.K., Deep, A. and Jain, N.K., 2024. Xplainable AI for deep learning model on PCOD analysis. In XAI Based Intelligent Systems for Society 5.0 (pp. 131-152). Elsevier.
34. Citron, N., 2022. The Role of Disclosure and Social Support on Quality of Life in Women with Polycystic Ovary Syndrome (PCOS) (Master's thesis, University of Windsor (Canada)).
35. Liu, T., Li, B., Yang, L., Qiao, J. and Chen, W., 2023. Tightly coupled integration of GNSS/UWB/VIO for reliable and seamless positioning. IEEE Transactions on Intelligent Transportation Systems.
36. Suha, S.A. and Islam, M.N., 2023. Exploring the dominant features and data-driven detection of polycystic ovary syndrome through modified stacking ensemble machine learning technique. Heliyon, 9(3).
37. Dutta, P., Paul, S. and Majumder, M., 2021. An efficient SMOTE based machine learning classification for prediction & detection of PCOS.
38. Kapadia, D. and Jain, R., 2023, November. Pcos Prediction: Advancements in Medical Informatics Using Artificial Intelligence. In 2023 2nd International Conference on Futuristic Technologies (INCOFT) (pp. 1-5). IEEE.
39. Chitra, P., Srilatha, K., Sumathi, M., Jayasudha, F.V., Bernatin, T. and Jagadeesh, M., 2023, March. Classification of ultrasound pcos image using deep learning based hybrid models. In 2023 Second International Conference on Electronics and Renewable Systems (ICEARS) (pp. 1389-1394). IEEE.
40. Vats, S., Sengupta, A., Chaurasia, A. and Narad, P., 2022. Combination of Expression Data and Predictive Modelling for Polycystic Ovary Disease and Assessing Risk of Infertility Using Machine Learning Techniques. In Innovations in Computational Intelligence and Computer Vision: Proceedings of ICICV 2021 (pp. 547-555). Singapore: Springer Nature Singapore.
41. Pathak, H., Handa, P. and Goel, N., 2023, December. Comparative Analysis of Feature Selection Methods for Automatic Classification of PCOD. In 2023 10th IEEE Uttar Pradesh Section International Conference on Electrical, Electronics and Computer Engineering (UPCON) (Vol. 10, pp. 235-241). IEEE.
42. Sinthia, G., Poovizhi, T. and Khilar, R., 2022. Analysis on polycystic ovarian syndrome and comparative study of different machine learning algorithms. In Advances in Intelligent Computing and Communication: Proceedings of ICAC 2021 (pp. 191-196). Singapore: Springer Nature Singapore.
43. Elmannai, H., El-Rashidy, N., Mashal, I., Alohali, M.A., Farag, S., El-Sappagh, S. and Saleh, H., 2023. Polycystic ovary syndrome detection machine learning model based on optimized feature selection and explainable artificial intelligence. Diagnostics, 13(8), p.1506.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

