ALN: An Anatomy-Aware Network For Unified Full-Volume Liver And Tumour Segmentation In CT
DOI:
https://doi.org/10.29284/jk9y5e12Keywords:
Liver tumour segmentation; computed tomography; full volume learning; Medical Segmentation Decathlon.Abstract
Accurate joint segmentation of the liver and intra hepatic tumours from computed tomography images remains challenging due to extreme class imbalance, scale disparity, and structural ambiguity of sparse lesions. Existing methods frequently prioritise liver delineation, rely on cascaded pipelines that propagate errors, or optimise solely for overlap based metrics that fail to preserve tumour morphology and suppress false positive leakage. This work proposes ALN, an anatomy aware liver network for unified full volume liver tumour segmentation that jointly models organ level context and tumour specific structure within a single end to end framework. ALN employs a shared volumetric backbone with dual semantic and structural heads and is optimised using a composite objective that integrates multi class and class specific Dice supervision, tumour focused focal loss, explicit background suppression, and structure aware constraints to stabilise learning under severe sparsity. Evaluation on the Medical Segmentation Decathlon Task03 Liver dataset using volume level inference demonstrates near ceiling liver delineation with a Dice score of 0.98 ± 0.01 and robust tumour segmentation with a Dice score of 0.86 ± 0.04, accompanied by balanced tumour precision and recall of 0.88 ± 0.05 and 0.85 ± 0.06, respectively. Ablation analysis confirms that each component of the composite objective and the structural supervision head contributes to improved tumour segmentation stability and balanced precision–recall behaviour.
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This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

